{"id":3883,"date":"2016-02-24T09:18:16","date_gmt":"2016-02-24T08:18:16","guid":{"rendered":"http:\/\/cienciagandia.webs.upv.es\/en\/?p=3883"},"modified":"2016-02-24T10:22:33","modified_gmt":"2016-02-24T09:22:33","slug":"new-device-for-early-diagnosis-of-cardiovascular-diseases","status":"publish","type":"post","link":"https:\/\/cienciagandia.webs.upv.es\/en\/2016\/02\/new-device-for-early-diagnosis-of-cardiovascular-diseases\/","title":{"rendered":"New Device for Early Diagnosis of Cardiovascular Diseases"},"content":{"rendered":"

The Nanophotonics Technology Center<\/strong><\/a> (NTC) of the Universitat Polit\u00e8cnica de Val\u00e8ncia is spearheading the PHOCNOSIS<\/strong> European project, whose aim is to develop a new portable and user-friendly device for early diagnosis of cardiovascular diseases<\/strong>. The project also incorporates the SYM group from the Center for Molecular Recognition and Technological Development<\/strong> as a second partner of the UPV. PHOCNOSIS launched in September 2015 and will continue running through to August 2018<\/strong>.<\/p>\n

RAPID, ULTRASENSITIVE AND SIMULTANEOUS DETECTION<\/p>\n

According to Jaime Garcia<\/strong><\/a>, project coordinator and research scientist at the Campus Gandia<\/strong>, the device he is working on aims to facilitate rapid detection – fewer than 10 minutes<\/strong> -and is ultra-sensitive, does not use markers<\/strong> (label-free) and can be used simultaneously with different cardiac biomarkers of relevance (several types of troponin-reactive protein C, etc.), by analyzing only a few drops of the patient’s blood<\/strong>.<\/p>\n

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It will be based mainly on the combination of two advanced nanotechnology concepts, key to achieving a compact and highly sensitivity final system. “First, we will make use of a micro-nanofluidic system<\/strong> to separate, purify and concentrate the biomarkers we want to detect. Subsequently, these concentrated biomarkers will be detected using a new nanophotonic sensing technique<\/strong> whose aim is to achieve final detection limits below 1 ng\/L,\u201d,says Jaime Garc\u00eda.<\/p>\n

With regard to price<\/strong>, the research scientist points out that the objective is for the cost of chip production<\/strong> – which integrate the photonic sensor and the concentration\/purification systems – to be<\/strong> lower than 3 euros<\/strong> and the reading device to be lower than 3,000 euros.\"phocnosis<\/p>\n

“This POC (point-of-care) device will significantly help to implement mass screening programs, with the subsequent impact on healthcare management and on reducing the cost of treatment<\/strong>,\u201d added Garcia.<\/p>\n

The PHOCNOSIS<\/strong> project is funded by the European Union Horizon 2020 program<\/strong>. The Polytechnic University of Valencia is partnering with Bionos Biotech SL\u00a0 and Genera Biotech SL (Spain); Fraunhofer-Gesellschaft and CDA GmbH (Germany); University of Twente (Netherlands); University of Aalborg (Denmark); EV Group GmbH (Austria); Art of Technology AG (Switzerland); and St. George University of London (UK).